I did notice on my Firefox 3.6.16 and Firefox 4 Beta -- running on 64-bit Windows 7, -- that often the text-format settings to my posts weird out. Firefox 3.6.16 is by far my primary browser, but I will try the boards with a couple of my other web browsers: Google Chrome 10.0.648.204, and Opera 11.01. I also have the current Safari and the latest, but not greatest, Internet Explorer. Also in the arsenal is Mozilla's Sea Monkey 2.0.13, but I'm not one for those "email client and web browser all-in-one apps."
After being a Macintosh user since 1985 and switching to Windows in 2009, I've just gotten used to conventionally placed menus. That's a one thing about Google Chrome that "kind of" slows me down. But If I used it more, I'd get more "used to that." But, I will say Chrome is fairly peppy and lean.
And I run the latest Java updates as they become available.
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Sidenote: I use Firefox mainly because of its expansion capabilities. I prefer the Mozilla suite of apps, and once I used Thunderbird 3.x.x for email, I never looked back. By the way, those used to using Apple iTunes on Windows may want to try Songbird for online streaming and music playing. It also has a fairly good HTML browser built-in as well. But getting it to support flash and Silverlite are another story.